How can the activating effect of the -NH2 group in aniline be controlled to prepare monosubstituted

Q: What is the correct answer for CBSE12?

The correct answer is B. The very high reactivity of aromatic amines in electrophilic substitution can be controlled by protecting the -NH2 group through acetylation with acetic anhydride. This reduces the activating effect, allowing for controlled monosubstitution, followed by hydrolysis to regenerate the amine.

Q: How can the activating effect of the -NH2 group in aniline be controlled to prepare monosubstituted aniline derivatives?

The correct answer is B. The very high reactivity of aromatic amines in electrophilic substitution can be controlled by protecting the -NH2 group through acetylation with acetic anhydride. This reduces the activating effect, allowing for controlled monosubstitution, followed by hydrolysis to regenerate the amine.

Q: What are the options for this CBSE12 question?

A. By direct nitration. · B. By protecting the -NH2 group through acetylation. · C. By using a strong oxidizing agent. · D. By performing the reaction at very high temperatures.

Question

How can the activating effect of the -NH2 group in aniline be controlled to prepare monosubstituted aniline derivatives?

FirstInTest · Accepted Answer

The very high reactivity of aromatic amines in electrophilic substitution can be controlled by protecting the -NH2 group through acetylation with acetic anhydride. This reduces the activating effect, allowing for controlled monosubstitution, followed by hydrolysis to regenerate the amine.

Answer

By direct nitration.

Answer

By protecting the -NH2 group through acetylation.

Answer

By using a strong oxidizing agent.

Answer

By performing the reaction at very high temperatures.

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